She is supposed to go from 2 to 1 a day in 3 days. Yeh! She has had none of the issues above. THIS MED IS AWFUL & I SO WISHED I NEVER GAVE IT TO HIM!!!! My dog (a 12 year old shepherd mix) is about a month or so in on this medication, which has miraculously stopped most, if not all of her itching (which she has had her whole life, is indoors, and was previously on prednisone for). He now has a tumor on his neck ( just removed and sent for histopatholgy). After reading all the complants. At the onset of all this she started behaving very depressed. I can’t wait for “winter” so I can see if I can take him off Apoquel and see if his weight goes down. Within the first 12 hours he developed runny poop and lethargy. My dog was on Apoquel for several months. He has been lethargic, urinating more then usual. During this time we went back to the vet for guidance and he was put on Prozac for dogs. AJR Am J Roentgenol 1984; 143: 509–517. Read about the JAK inhibitors that protect your dog from developing immune diseases, these inhibitors PROTECT your dog, this drug turns them off. That is sad. Thanks again Dr. Jones. Itching caused by an allergic skin disease can be an Keep in mind she has been on the Apoquel since the spring of 2014 when it came out. Apoquel helps him -100%, bur increase thirst and he urinated more often then normally. Shes been fine since I took her off of it. He kept breaking out in scabby smelly yeasty sores which would eventually turn the skin black and constantly itching and scratching. I called the vet and was informed to “Keep her on the Apoquel and give her boiled rice and chicken for her vomiting.” I gave her the boiled rice and chicken but I immediately took her off of the Apoquel and her vomiting stopped. My dog is much worse now and has a tumor under her forearm. After reading almost all of the comments on here I would think you would all exchange info and file a Class Action Lawsuit against the makers of this drug, the FDA for negligence, at least. This year is especially bad. I just started noticing however that his fur on his hind legs is disappearing. APOQUEL (oclacitinib) manufactured by Zoetis, I took him to my vet and he put him on Doxycycline. Then he began acting weird one day starting with having diarrhea then he started panting, drooling, pacing, sitting on my chest I knew something was wrong and went to the animal emergency room. Both dogs are back to normal and learning to like the regular baths, (with at treat at the end). He is asking to go out to pee a lot more than he used to and now has developed a smell similar to mild cat pee (no cats in our home). Best regards Thanks to all for yoru comments. I’ve made a official complaint against the vet that proscribed this poison only to be told that seizures are not a side effect of Apoquel the vets take no responsibility for my dogs death. Then came the seizure. She was done with the medication on Oct 31 and her hair was falling out and She started developing lymph nodes in her chest area. We lost our Ginny girl. I’ve learned in my research today that this adverse effect is actually happening somewhat frequently, or rather, I’ve found many reports from pet owners who’s dogs had this reaction. The above mentioned worked but she also added Atopica for 3 – 5 months to sustain the gut so he wouldn’t itch anymore. I ended up at the emergency hospital where he was put on antibiotics, IV’s and had X-rays, bloods and ultrasounds done. I wasn’t told about these side affects nor given a handout. Now we will take her to Neurologist. Shame on me for not doing my research. I knew the potential for problems but was willing to do anything make her comfortable, and hoped that she would not show any negative effects. My dog was given this because it was said to work faster. Our girl is a 14 pound Yorkipoo. This new vet prescribed Aproquel 16mg (twice daily 14 day supply) for a chronic allergy problem, we think from the cat. I chose to start frequent washing with 3% BPO shampoo to deal with the yeast infections from allergies, (at least thats what the vet told me was causing this). We did try a restricted diet and the diet didn’t affect his scratching. Thank you all for sharing. The most horrible thing I was witness to.His right eye sunk in to his skull. term side effects by shutting down immune system. A couple of weeks later, she called me and talked me into starting him on 1/2 dose as the hydroxizine wasn’t working. I am seriously thinking this drug is to blame. She is on Revolution and I have never seen a flea on her. my point is for 3 yrs she had to be kept on prednisone and antibiotics. Full Year 2014 Revenue of $4.8 Billion Increased 5%; Adjusted Net Income of $790 Million, or Adjusted Diluted EPS1 of $1.57, Increased 11% Last year we tried Apoquel. Since August 2018 when we discontinued giving Aries Apoquel, there are a few papillomas of small size but nothing like was spreading all over his body. He can’t come down the stairs or jump on the bed. He is nibbling them constantly. They were both prescribed Apoquell July 2016 over the next few months one dog developed two small growths on his feet that were removed and one found to be malignant the other benign. We finally got to take his cone off and start to enjoy walks again fully and his paws turned back to their original color–white! The Apoquel seemed to work like magic. Keep fighting the good fight! After several visits to the veterinary center and medications including certrizine, hydroxyzine, loratadine, prednisone the veterinarian suggested trying Apoquel in December 2016. Translating the above means that for the first 2 weeks of medication the most common side effects are gastro-intestinal ( vomiting/diarrhea), BUT after 2 weeks, there are measurable blood value changes. Within a day he had lost his appetite and was less playful than usual. She ended up on 2 antibiotics and eye drop for 3-4 weeks. Sure, it notes side effects, but the drug didn’t “cause” mange. He has always had a scratching, itching biting skin problem. My 12 1/2 yr old westie has been very healthy for his whole life until last august . Working very well for paw licking, but like others, he has to pee all the time and did so in the house yesterday (something he NEVER does). It’s like there is flem in is throat and he can’t catch his breath. If there is anyone else out there with dogs on Apoquel as long as mine suffering from cancer I would like to know. Don’t listen to what your vet says, arm yourself with knowledge by researching this and everything else they say, you’re lining their pockets, they have a business to run and the companies that make these drugs have profits to make, do you really think they want you to have a healthy dog? Please do not give your dog this medicine I know it makes him stop itching but the outcome is not worth it putting him to sleep, it’s like putting your child asleep. Recently we moved to a different side of town in a metropolitan area and needed to find a new vet. No way will I us it.Thank you every one for opening my eyes. I took her outside to see if she needed to potty, but she didn’t really need to. He still has the runs. She was allergic to grass and any food that was not grain free. one-sixth the normal dose (1/2 tablet a day), he was unable to walk at all, and he developed increased thirst and increased urination Bit worried my E.R. Great! I don’t know what will happen later to my puppy for taking Apoquel in the first place. Our friend was aware of the allergy and per her normal vet was doing a process of elimination with his food, treats, shampoo, etc. My Ginny was placed in ICU to help regulate her breathing. This medication is not worth your puppy’s life. She gave my dog Prince Si Miao Four Marvels Formula (can buy this online) I gave a 1/4 or less amount that a human would take for 4 months (herbs must be watched not to take for long periods of time so look for any side effects like blood in stool) . I have a three year old yorkie mix, about 30 pounds who is an Hospice therapy dog. looks great but also is sseems to want more attention than usual He has had these issues his whole life (and in the last two years we have moved two hours away). I had tried hydroxyzine I think it is and now am trying the apoquel. At the beginning of Spring of this year. The vets are making a fortune off this drug and the injections that is why they are pushing them. The new vet recommended apoquel after a while he claimed it had zero side effects and many of his patients said it was a miracle drug. I feel apoquel has destroyed his ability to fight infections as before Ollie always responded well to treatments and now not at all. Sooooo happy with it… but… All of a sudden, she has developed a whole new set of even more significant and really scary issues: She started going “kiki” accidentally, when she would start “digging” on furniture, in bed, where ever! The day I bought the second months prescription at the cost of $105 my dog began having bloody diareah. Fourth Quarter 2014 Adjusted Net Income of $203 Million, or Adjusted Diluted EPS1 Thanks everyone! He’s been to Cornell, and we have tried just about everything. I was at my wits end after failing to relieve his itch, but I refuse to subject my love to seizures and liver damage. Avoid synthetic drugs unless there is no other way. Brief in length, 5 minutes. I have two westies on apoquel, both have problem skin. I’m convinced it’s from this med!!! I find that hydroxyzine work best for my girl but that requires an Rx. Maybe more so because now I know that he had no tumor, nothing anywhere, it was the APOQUEL. We’re here at the next morning and she seems a tiny bit more alert. I ran to the vet and asked for more…$55 later, I had another months supply. …..for a few weeks. Luckily the infection resolved without injury to her eyelid or sight. My 15l.b Westie has been on Apoquel 3.6mg, twice daily since Jan.2016. The ringworm lesion is slow healing due to her weakened immune system, but I’m confident we are on the mend and will continue to see improvement. What should I do ? Finally the neurologist did and MRI and found no stroke, no tumor, her blood vessels looked good and she was over 6 yrs old. My 6 year old french bull dog was put on Apoquel on 17/3/17 he had his first seizure on 2/4/17 he passed away on 4/4/17 my dog was fit and healthy up till his first seizure. This dog was perfectly healthy and suddenly went down hill. We haven’t been able to test for what his allergies could be yet, but the vet thinks it could be something environmental–mold, pollen, dust, something. It is disturbing to realize that others have had almost the same situation. Two days after being on Apoquel, we noticed less itching. I found out about this drug here and on other web sites. Is it okay to take her off immediately, or do I need to wean her gradually? Bloods came back as normal and vet said it wasn’t the Apoquel that caused the fits. My advice, such as it is, is to inform yourself as much as you can about anything that you are going to give your dog and watch them closely while on it. I forgot you add the above food mix to 3kg of chicken or turkey mince. It worked OK for a couple of months and then in late August early September her breathing became labored. Fourth Quarter 2014 Revenue of $1.3 Billion Increased 5% Compared to Fourth Quarter 2013 We even had a needle biopsy done. It’s nice to see her not so stressed out over scratching and with a beauriful full coat. IV or liposomal? I have read some of the negative comments here and all I can say is… The veterinarian explained he was born with this and it will manifest when his immune system is weaken. Very unlike him and the bowl belongs to a dog that visits a lot and he is head over heels in love with. All in all, very mild side effects as opposed to other anti-pruritic medication. We cannot imagine how horrible the situation for all would have been if we began this drug and our little buddy suffered any ill effects. They say it can take a month per year of your pets life to work. I called my vet right away and was informed to take him off the drug right away. Nothing processed, out of a can or a bag, no dry food ever (it’s basically rubbish anyhow). Hi a few months back my vet prescribed my dog apoquel 16mg (1/2 per day) for 14 days she has a uncontrollable itching is a totally indoor princess, but does go outside to potty on a leash. I am not a vet, just an educated pet owner who totally gets how frustrating it is to have an itchy dog. What kind of a vet would put a dog on a drug that Metacam – with known renal and liver side effects. Please be aware and do your homework on this drug. When we arrived, Ginny pooped alot which I thought was because of the travel. Although there is no way of knowing for certain if the drug Apoquel is responsible for what I am seeing with my dog, I am going to stop the drug altogether. Does anyone else experience these symptoms? NO MORE DRUGS FOR THESE GUYS. I have also noted some days he does not want to eat. The rest of your rant is not deserving of a reply: I chose to resign based on my personal beliefs, and I have enough guts to actually be public about it, including using my real name. When we moved my new vet recommended the new drug that was having great results on allergies in dogs – Apoquel. I just think until you have an allergic dog, “you” are unaware how wide spread of a problem it is. He’s on IV fluids but not expected to live more than a week. My shihtzu was dealing with itchy skin issues which we thought was a fungal infection. Liver counts are high is some areas so we will check again in two months. Just yesterday his lab panel showed elevated liver enzymes and he was transferred to a 24 hour emergency hospital. Lastly, I think you choose to bash a drug just to sell your supplement. The first 30 days there seemed to be no side effects, his appetite was good and it stopped the itching immediately upon the first dose he received. My 4 year old Yorkie was put on apoquel. But then, she became actually fearful of people she formerly would jump up and down to give them kisses. It was attached to the muscle and she didn’t cut into it because of the location of the tumor. My 15 year old Cairn developed environmental allergies when she moved to CT from FL. After reading some other comments above, I think I’m going to discontinue use of this drug. I wish I could turn back time because I have caused permanent damage to my dog, and I am heartbroken over it. My Chow has now been on Apoquel for less than 48 hours. He has now lost hair all over his body. My Mattie, a 13-14 year old shih tzu rescue, was put to rest on July 16th. This drug should be taken off the market! I am going to let my Vet know. !!! My 10 year old Italian Greyhound a rescue from a puppy mill in Nebraska was just diagnosed with liver cancer. I knew all the side effects and finally was relieved to try the apoquel against my better judgement. She would itch and get staph infections. My 7 year old male GSD has been on apoquel for 2+ years now for horrible scratching due to atopic dermatitis. Too few veterinarians are explaining the risks. blood present), urinary tract infections, aggressive behavior, I bathe her twice a month too. I was aware of the risks involved with this drug and was well informed both by my vet and also by my own research before beginning his treatment. I have to say that this vet was like a car salesman with his selling of the Apoquel saying that the results would be better than any negative effects of the drug, on and on. Just please don’t pump them with drugs, there is no magic pill but with research I’m sure you too can find a natural solution that will help. He has food allergy tests done several years ago and is allergic to rice, peas, carrots and several other things. My dog had a history of pancreatitis, vet should have known this product and think this is not good for this dog. Her stays showed fluid in her heart area and fluid in her lungs. Died in hospital where we had to carry her. I found a Veterinarian that was also a Herbalist. If the wind blows the wrong way she starts breaking out. For slight allergies try otc antihistamines like Zyrtec. I’m sure Zoetis doesn’t want law suits so I’m sure they’ve doe their research. Fuck this drug. The vet call the Apoquel He had been on it continually for about two/three years as I was I informed that there was no serious side effects and that it could be used for as long as it was working. He was diagnosed with severe pancreatitis. This is also holistic and works by making the yeast exit the body through the hair follicles. He is so sick he can’t pick his head up. Nowhere in the FDA stats on Apoquel does it claim that Apoquel “is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection”. Vet said to try him on Apoquel. But because he was itching excessively, the Vet prescribed Apoquel. Today I’m contacting the FDA to self report these side effects. Took him to the vet today and he has kidney failure. She was perfectly healthy and just a few weeks of the med and now she is gone, she was only 11. He had an ultrasound and it was determined it was likely due to the Apoquel, and he was diagnosed with liver disease. I didn’t get a refill. I don’t believe it. When we found the new vet he said he wanted to try Peatie on a new anti-itch drug…pricey but effective. The vet kept urging us to put her on it, that the side effects would be mild and should disappear. After reading the comments here I will not be continuing on Apoquel. Being very worried, I began doing research on the Apoquel the vet had given her and was shocked to find out its an immunosuppressant with some ugly side effects. The vet recommended Apoquel “new improved antihistamine drug”. This medicine stopped the itch and it had wonderful results UNTIL recently she had 2 seizures!!!! can respond inappropriately, and may begin attacking the I am certain that Apoquel caused this problem. Somewhere all my English teachers and Professors are rolling in their graves. We have a rescue dog, 3 yrs old now. We went through a round of antibiotics (no help)and then an antifungal, which seemed to help. NONE OF THESE SO-CALLED VETS EVEN eat, no appetite, and started throwing up. She is now on hydroxizine and it is at least as effective without the immune suppression and horrible risks. 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