Severe toxic effects can occur but are rare. Note: Do not give your dog theophylline unless it has been recommended by your vet, and always follow the vet’s exact dosing recommendations. If they are not available, follow their directions in contacting an emergency facility. Contributors: Rania Gollakner, BS, DVM, MPH. Dog owners who have mostly had large breed dogs may have less chance to be familiar with a tracheal collapse or similar conditions. Many drugs are commonly prescribed for off label use in veterinary medicine. It is also sometimes used as adjunctive therapy for pulmonary edema and bronchoconstriction at a dosage of 1.8 – 4.5 mg/lb three times daily. Dextromethorphan is given by mouth and is used off label to treat compulsive behaviors and occasionally used to treat cough. This form of treatment usually improves a dog’s condition quickly. Side effects of prednisone in dogs may include increased thirst and hunger, panting, a loss of energy, vomiting, and/or skin infections. Your doctor can recommend the proper treatment and let you know about any potential side effects to watch out for. Older dogs tend to take longer to clear the drug which should also be taken into account. Because the drug is not very soluble in fat, it may be necessary to dose by lean body weight in very overweight dogs. Theophylline is a bronchodilator, which a veterinarian may prescribe for your pooch to help relax her airways. Cette action aide à soulager les symptômes liés à des problèmes respiratoires, notamment une toux, une respiration sifflante et un essoufflement. If a negative reaction occurs, please call your veterinary office. Overdose: Contact your veterinarian immediately if you observe these side effects in your pet. It opens the lung’s air passages by relaxing the muscles in the lungs and chest. If a negative reaction occurs, please call your veterinary office. Veterinarian approved Respiratory Support products. Normal Joints Look Like this in Dogs and Cats . Theophylline (brand names: Theo-24®, Theochron®, Elixophyllin®, Theodur®) is a bronchodilator used to treat coughs caused by bronchospasm or bronchoconstriction. It also has mild diuretic effects. Nosebleed: First Aid. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, sleepiness, drooling or anxiousness. It is important that these pills are not chewed or crushed. Nebulizer Use for Dogs and Cats. We’re committed to keeping clients and staff safe during COVID-19 with NEW admittance and check-out processes. Sources Theophylline does not work immediately; Do not use it to relieve sudden breathing problems like asthma or bronchospasm attack. Tse, 1 *x Daniel W. Szeto, 1 ‡ 1 College of Pharmacy, Rutgers—The State University, Piscataway, NJ 08854 College of Pharmacy, Rutgers—The State University Piscataway NJ 08854 * Drug Metabolism Section, Sandoz Pharmaceuticals, East Hanover, NJ 07936 Drug Metabolism Section, Sandoz Pharmaceuticals East … However dogs with the following conditions may not be suitable for treatment: Theophylline interacts with other medicines including some antibiotics, thyroid medication, furosemide, phenobarbital, and many more. Give as directed by your veterinarian. The following information is provided as a general guideline only. Included in the drug classification as smooth muscle relaxant, the medication is active against conditions affecting the respiratory muscles of dogs and cats. MRSP Dogs and Spaying. Theophylline, also known as 1,3-dimethylxanthine, is a phosphodiesterase inhibiting drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. If your dog has been prescribed prednisone, keep close watch for any of these reactions, especially within the first few days. For example, at 8 am and 8 pm each day. In these instances, follow your veterinarian’s directions and cautions very carefully as their directions may be significantly different from those on the label. Notes Theophylline Bioavailability in the Dog Francis L.S. Pets with liver disease or heart failure should receive lower doses of the medication. The dosage should be adjusted carefully to balance the side effects with the effectiveness. If stomach upset occurs on an empty stomach, give the medication with food. My 7 year old dog was accidentally given her Theophylline Medication too early today. Ventricular fibrillation was induced in three of eight dogs given a toxic dose of theophylline. Reply. up for it. During treatment the dog will need to be carefully monitored, both for the relief of symptoms, and for how well he tolerates the drug. Keeping your Pet Healthy and Happy. Dog owners are often times worried about their dog panting at night. These signs include seizures and collapse and may indicate that the dose of theophylline is too high. Theophylline is also used to treat both dogs and cats with collapsing trachea, intrathoracic airway collapse and pulmonary edema. Do not use in pets that are allergic to it or other opioids, in pets with inflammatory bowel disease, or in pets that have ingested a toxic substance. The chart and calculator below should help you find the typical starting dose for your dog. Theophylline is available in several formulations, including injectable, aqueous solutions, elixirs, tablets, and capsules. It is a bronchodilator used to reduce inflammation and swelling of muscles in the lungs and chest. Though toxicity in humans starts when blood levels of the drug rise above 20 mcg/mL, dogs are better able to tolerate higher levels. In both human and animal studies, aminophylline significantly enhanced conduction in atrial and ventricular tissue. One possible treatment option if seizures occur is to administer Valium (diazepam) intravenously, while keeping the airway open. Theophylline is given by mouth in the form of a tablet or liquid, with or without food. It’s best to give the medicine with food to help avoid vomiting. Every once in a while she does take a deep breath but it seems forced. Theophylline is an oral medication used to treat asthma and other lung diseases. My husband forgot that she got her morning meds at 2:00 p.m. today. Aminophylline is a theophylline salt that is 78%–86% theophylline. Theophylline is available in a range of formulations, including tablet, capsule, and oral liquid. Theophylline is used in situations that require dilation of the airways. She sleeps with very shallow and short breaths. Panting is considered abnormal when it occurs for reasons other than heat dissipation, and can be recognized by one or more of the following characteristics: Appears excessive compared to the dog’s normal panting pattern; Occurs at inappropriate times (when the dog is not overly warm) Sounds raspier, louder, or harsher than normal Panting in dogs at night may be as a result of the room being too warm. ©Copyright VCA Hospitals all rights reserved. Theophylline Aminophylline is a combination of theophylline and ethylenediamine. Recovery of Meloxicam Poisoning in Dogs. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. Learn who it’s for, how it works, its side effects, warnings, and more. If she isn't on an antihistamine then trying benedryl at a dose of 1mg/pound may benefit her and it won't hurt to try to see if it helps. Give it to her three times a day. Long-acting bronchodilators, such as theophylline or prednisone, often are given orally for an extended period of time. Theophylline tablets or oral liquid should be stored at room temperature, below 30°C (86°F), in a tightly closed container. Often, these can be avoided by starting initially at a dose of 5 mg/kg PO BID for a few days, then increasing the dose to 10 mg/kg PO BID if the dog tolerates it. See your veterinarian if your furry friend displays any asthma-like symptoms. Its use in cats and dogs to treat cough and bronchoconstriction is 'off label' or 'extra label. A liquid form sold under the trade name Elixophyllin is also available, containing 5.3 mg of theophylline per milliliter. Theophylline is a prescription medication that’s used to treat asthmatic bronchitis, chronic obstructive pulmonary disease and congestive heart failure in dogs. Metacam has been approved for dogs, but there are still certain risks with taking it. Theophylline is a medication closely related to caffeine. This syndrome occurs when a dog’s adrenal glands produce too much cortisol. Never give your pet two doses at once or give extra doses. This medication should take effect within 1 to 2 days, and you should see improvements in your pet’s clinical signs. Give this medication to your pet exactly as your veterinarian prescribes. Take the tablets/capsules exactly as your doctor tells you to. Other side effects include sleeplessness, increased drinking, eating, and urinating. Theophylline can actually improve breathing but also create anxiety or agitation which may be seen with panting. Do not crush or break the tablets or allow your pet to chew them. Theophylline is sometimes given to dogs to treat the following conditions: Not much is yet known about the adverse effects of this medicine, but the following effects are possible: Symptoms of nervous system excitement (such as anxiety and insomnia) and stomach upset tend to pass with repeated use and adjustment of the dosage. The medicine is usually given to dogs at a dosage of 4.5 – 6.8 mg/lb every 12 hours (twice daily), or 9 mg/lb once daily using 24-hour extended-release pills. Reply . Theophylline should not be used in pets that are sensitive or allergic to it, or related substances such as theobromine, aminophylline, or caffeine. Always seek emergency advice if you suspect an overdose, either by calling your vet or the ASPCA poison control hotline on (888) 426-4435. Chronic bronchitis and other airway diseases in dogs Il s'agit de la 1,3-diméthyl xanthine. La théophylline appartient à la classe des médicaments appelés bronchodilatateurs. Dosing can be adjusted as needed under the direction of your veterinarian, with a typical dose being 100mg twice a day. And he gave her night time meds (which are given to her at her dinner time) at 8:00 p.m. tonight. The steroid will affect each dog differently so you can’t fully predict how your dog will react. SHe JUST began taking 300 mg. of Theophylline twice daily yesterday. The condition can be serious, even life-threatening. Your pup also may eat, drink and urinate more often than usual or experience some stomach upset. Note: Do not give your dog theophylline unless it has been recommended by your vet, and always follow the vet’s exact dosing recommendations. Affected dogs, who are usually middle-aged or older, tend to pant more, drink more, urinate more and want to eat more. Theophylline is used as a bronchodilator in dogs and cats with asthma or other respiratory conditions. If she becomes more anxious while on it (a possible side effect) then it just negates the reason for trying it and you may need to try a different … Elle s'utilise pour soigner des affections respiratoires comme l'asthme, l'emphysème et la bronchite chronique. http://www.veterinarysecrets.com/newsIn this video Dr Jones shows you all the common reasons for dog panting. Theophylline has variable metabolism across individuals, and side effects include vomiting, diarrhea and agitation. It is extremely important to administer the medication exactly as prescribed by the veterinarian. You should contact your veterinar- ian before switching brands once your animal is controlled. Elle est également présente entre autres dans le café, le chocolat, le maté et le guarana. It should be used with caution in pets with severe heart disease, abnormal heart rhythms, seizures, stomach ulcers, hyperthyroidism, kidney or liver disease, severely high blood pressure, or severely low blood oxygen levels. It also has mild diuretic effects. In some cases, blood levels of the medication may be monitored to be sure the dose is correct. Do not use in pets that are allergic to it. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver disease or congestive heart failure. Use a fast-acting inhalation medication if sudden shortness of breath occurs. Once your dog begins treatment, the elimination of fluids will be obvious, evident in the form of a dog urinating in abundance. Symptoms such as restlessness and stomach upset may subside after around two weeks, as your pup's … Theophylline is used as a bronchodilator in both dogs and cats to treat bronchoconstriction and inflammation associated with chronic inflammatory lower airway disease and feline asthma. For twice daily doses, always try to take your doses 12 hours apart and at the same times each day. It may also be used with other medications in the treatment of cardiac disease. Electrolytes, fluid and heart function will be closely monitored following an overdose. La théophylline est un alcaloïde du type méthylxanthine. My dog is small and so only give him half or quarter 20mg tablet. It is very practical and goes over details that get missed in our curriculum. Nutrition and Exercise for … Your pet should be monitored for signs of toxicity. What is Theophylline? Microchipping Could Save your Pet's Life. The most common symptom of overdose is a rapid heart rate, and apart from this, seizures, hyperthermia and arrhythmias are possible. Jerky Dog Treats from China may be Associated with Kidney Issues. 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